So yeah I have been really slacking on the blogging. I am onto F3 generation. I was having no luck on producing a rabbit with both the Lutino coloring and rex fur. I took the Lutinos I had and bred them all to Mini Rex. This is because I had no idea if they carried rex so I figured breeding to rex would accomplish two things. 1. Test for the rex gene and 2. Make rex Lutino carriers. I was successful in producing two rex coated Lutino carriers. They are siblings but will likely be bred together which will produce 100% rex with some also being Lutino. Wish me luck!
I will update the page with the current Lutino breeding stock here at Berlena's. Thanks for reading and leave a comment to let me know if anyone reads this stuff!
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Lucy kindled her first live litter! Her first time resulted in three DOA kits. This time she had two live. I suspect the light one may be a Lutino...fingers crossed!
I sexed Zodiac's litter. I found three bucks and three does.
Now to wait about 5 months to be able to breed offspring from both litters together. Hopefully I can get both rex coat and lutino on the same rabbit early on! It has been a while since I've updated this blog.
Fawn kindled a singleton and its a normal coated broken chestnut doe which I call "Lucy". Soon after I bred a big broken black doe named Zodiac to Bloodshot and she has a large litter of seven, all broken chestnuts except one broken black. Eventually I plan to breed Lucy with a buck from Zodiac's litter. The lutino coloration is called a "p mutation" because of an integral membrane p protein. The p-protein appears to be a transporter, however for exactly what remains unknown. Because high levels of tyrosine induce pigmentation in the eye’s melanocytes it would suggest this p protein plays a role in tyrosine transport. It does not only affect the eye but coat color as well. It is recessive (so P is normal and p is the mutation) and a rabbit that is pp will have the pink eyes and also the fur color changes. In a sense, this mutation causes an effect similar to the non-extension gene, just to a less degree and with the addition of the pink eyes. This is due to the decreased production of eumelanin with yet little effect on pheomelanin. While there could be different variants, the basic orange colored lutinos are genetically A_B_C_D_eepp. Cream colored lutinos (called “Shadow”) and are genetically A_B_C_D_E_pp. The p mutation can create other colors with different base genotypes. This is not a "new" mutation. It is the one of the more common forms of albinism. The official name is type II oculocutaneous albinism. It is a Tyrosinase positive form. In mice, the protein product of this p locus’ first intraluminal loop was studied back in 1994. In mice, William Castle wrote about it in 1909. So as one can see, this has been a long studied mutation. However, we still have a lot to learn about exactly what this transport protein does and the exact mechanism by which it works. 1. Rosemblat, Susana. et al. Identification of a melanosomal membrane protein encoded by the pink-eyed dilution (type II oculocutaneous albinism) gene. PNAS. December 1994; 91: 12071-12075. 2. Russell, ES.Genetics 34: 146 March 1949 3. Castle, WE. The Peculiar Inheritance of Pink Eyes Among Colored Mice.Science. 3 September 1909; 30(766): 313-314. -------------------------------------------------- lu·ti·no /lo͞oˈtēnō/ : early 20th century: from Latin luteus ‘yellow’ + -ino, on the pattern of albino . I am very excited to find that Fawn palpated positive today to Bloodshot! Now I am hoping for a successful litter. It will be very interesting to see the offspring! They will have normal coats and will not be Lutino but will be carriers for the Lutino, dwarf, and rex genes! I expect reds and maybe fawns.
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Lutino MRFollow along as I attempt to create Lutino Mini Rex! Archives
September 2018
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